Progesterone
Micronized bioidentical progesterone to balance estrogen support and help with sleep.
What Progesterone is
Micronized progesterone is bioidentical to the progesterone your ovaries produced. In a hormone protocol it protects the uterine lining when you take estrogen, and many women find it steadies sleep and mood on its own. It is taken at bedtime because it can cause drowsiness. Your provider decides whether continuous or cyclic dosing fits you.
Who it may be appropriate for
- Women taking estradiol who have a uterus
- Women in perimenopause with sleep disruption, irregular cycles, or mood shifts
- Women who want a bioidentical option reviewed by a provider
Who it is not for
- Women with a history of breast cancer, blood clots, stroke, or liver disease
- Women with unexplained vaginal bleeding
- Anyone with a peanut allergy, for capsule formulations that contain peanut oil
Your protocol, over time
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1Week 1
Take it at bedtime. Drowsiness is expected and is why it is dosed at night.
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2Weeks 2 to 8
Sleep and mood often settle. Some spotting can occur while your body adjusts. Follow-up at 6 to 8 weeks.
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3Ongoing
Reviewed with your estradiol protocol every 6 months.
What your care team watches
Every protocol is built on labs and reviewed by a licensed provider. Your care team tracks these markers and flags anything that needs attention before you have to ask.
Read this before you begin
- Carries the same class boxed warnings as combined hormone therapy: cardiovascular events, stroke, blood clots, breast cancer, and probable dementia in women over 65 on combined therapy.
- Common side effects include drowsiness, dizziness, breast tenderness, bloating, and headache.
- Do not drive or operate machinery until you know how it affects you.
- Report unexplained vaginal bleeding, leg swelling, chest pain, or sudden headache immediately.
- Some capsules contain peanut oil. Tell your provider about any peanut allergy.
This is not a complete list of side effects, warnings, or interactions. Your provider will review your full history before prescribing and will provide complete medication information with your prescription. If you experience a medical emergency, call 911.
Frequently asked
Can I take it without estrogen?
Yes, in some perimenopause protocols. Your provider will decide based on your symptoms.
Why at bedtime?
It commonly causes drowsiness, which many women welcome as a sleep aid.
Is it the same as progestin in birth control?
No. Progestins are synthetic and act differently. Micronized progesterone is structurally identical to your own hormone.
Membership provides access to Fortem's clinical care platform and provider network. All medical decisions are made by licensed providers. Fortem Health does not practice medicine. Results vary by individual. This platform is not a substitute for emergency medical care. Medication availability depends on state licensing and clinical appropriateness.